Characterization of a Novel Murine Aldo-Keto Reductase
作者： Kurt M. Bohren , Oleg A. Barski , Kenneth H. Gabbay
DOI: 10.1007/978-1-4615-5871-2_52
关键词:
摘要: The aldo-keto reductase superfamily (Bohren et al., 1989) consists of many reductases that differ in their primary structure, substrate specficities and catalytic properties. Many subfamilies have been recognized, including the aldose reductase, aldehyde 3α-hydroxysteroid dehydrogenase, androgen regulated protein from mouse vas deferens, more. In course cloning murine liver reductases, we discovered yet another with some unique We hereby describe cloning, sequencing, over-expression characterization this novel which appears to be uniquely different any hitherto described member superfamily.
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