The Continuing Saga of the Marine Polyether Biotoxins

作者: K. C. Nicolaou , Michael O. Frederick , Robert J. Aversa

DOI: 10.1002/ANIE.200801696

关键词:

摘要: … The ladderlike molecular architecture of this fused polyether molecule, its potent toxicity, and … Of the marine polyethers, maitotoxin is not only the most complex and most toxic of the class…

参考文章(260)
Henri B. Kagan, Twenty-five years of organic chemistry with diiodosamarium: an overview Tetrahedron. ,vol. 59, pp. 10351- 10372 ,(2003) , 10.1016/J.TET.2003.09.101
T. R. Howard, J. B. Lee, R. H. Grubbs, Titanium metallacarbene-metallacyclobutane reactions: stepwise metathesis Journal of the American Chemical Society. ,vol. 102, pp. 6876- 6878 ,(1980) , 10.1021/JA00542A050
Masayuki Satake, Akio Morohashi, Hiroki Oguri, Tohru Oishi, Masahiro Hirama, Nobuyuki Harada, Takeshi Yasumoto, The Absolute Configuration of Ciguatoxin Journal of the American Chemical Society. ,vol. 119, pp. 11325- 11326 ,(1997) , 10.1021/JA972482T
Nobuyuki Hori, Hiroko Matsukura, Goh Matsuo, Tadashi Nakata, Efficient strategy for the iterative synthesis of trans-fused polycyclic ether via SmI2-induced reductive intramolecular cyclization Tetrahedron. ,vol. 58, pp. 1853- 1864 ,(2002) , 10.1016/S0040-4020(02)00042-X
Yuji Mori, Keisuke Yaegashi, Hiroshi Furukawa, Oxiranyl Anions in Organic Synthesis: Application to the Synthesis of Hemibrevetoxin B Journal of the American Chemical Society. ,vol. 119, pp. 4557- 4558 ,(1997) , 10.1021/JA9701523
K. C. Nicolaou, K. Raja Reddy, Golfo Skokotas, Fuminori Sato, Xiao Yi Xiao, C. K. Hwang, Total synthesis of hemibrevetoxin B and (7a.alpha.)-epi-hemibrevetoxin B Journal of the American Chemical Society. ,vol. 115, pp. 3558- 3575 ,(1993) , 10.1021/JA00062A021
Isao Kadota, Yoshinori Yamamoto, STEREOCONTROLLED TOTAL SYNTHESIS OF HEMIBREVETOXIN B Journal of Organic Chemistry. ,vol. 63, pp. 6597- 6606 ,(1998) , 10.1021/JO9807619
Masayuki Inoue, Masahiro Hirama, Total synthesis of ciguatoxin CTX3C, a causative toxin of ciguatera seafood poisoning Synlett. ,vol. 2004, pp. 577- 595 ,(2004) , 10.1055/S-2004-817767
Frank E. McDonald, Xia Wang, Bao Do, Kenneth I. Hardcastle, Synthesis of oxepanes and trans-fused bisoxepanes via biomimetic, endo-regioselective tandem oxacyclizations of polyepoxides. Organic Letters. ,vol. 2, pp. 2917- 2919 ,(2000) , 10.1021/OL0064009