Models of Luteinization

摘要: Luteinization is essential to the success of early gestation. It process by which elements ovarian follicle, usually including both theca interna and granulosa cells, are provoked ovulatory stimulus develop into corpus luteum. Although there significant species differences in luteinization, some pervade, morphological functional differentiation produce secrete progesterone. There evidence that luteinization results cell exit from cycle. The mechanisms appear control include intracellular signalling pathways, adhesion factors, cholesterol oxysterols, perhaps progesterone itself as a paracrine or intracrine regulator. Cell models along with conflicting observations on process, discussed this review.