作者: Magdalena Madero , Mark J Sarnak
DOI: 10.1097/MNH.0B013E328326F3DD
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摘要: PURPOSE OF REVIEW To discuss recent studies which have evaluated determinants of cystatin C and to focus on the relationship with mortality, cardiovascular disease (CVD), noncardiovascular outcomes. RECENT FINDINGS In Chronic Kidney Disease Epidemiology Study was associated demographic characteristics independent measured glomerular filtration rate (GFR), although this a smaller extent than creatinine. patients established chronic kidney (CKD), strongly inversely correlated GFR, suggesting that may other determinants, it is primarily measure function. Several cohort studies, particularly in older adults, now demonstrated linearly CVD non-CVD outcomes, whereas creatinine risk individuals more advanced disease. A study has also shown changes function as ascertained by C, even within relatively normal range, are subsequent all-cause mortality among adults. SUMMARY Cystatin appears capture an association mild increased Future should evaluate whether can improve medical decision-making lead favorable patient