Morphologische Veränderungen im ZNS bei Schizophrenie: Kernspintomographische Befunde und ihre Bedeutung
作者： Pfalkai Falkai , A. Schmitt , T. Wobrock , T. Schneider-Axmann , O. Gruber
DOI: 10.1007/978-3-211-92215-6_10
关键词:
摘要: Die Schizophrenie ist eine Netzwerkstorung, die sowohl kortikale als auch subkortikale Bereiche umfasst. Der vorliegende Beitrag fokussiert auf den Hippocampus, der zentral temporo-limbische Veranderungen bei widerspiegelt. Eine bilaterale Volumenreduktion des Hippocampus gehort zu am besten replizierten Befunden strukturellen Bildgebung (Nelson et al. 1998; Wright 2000; Velakoulis 2006). Obwohl sich dieser Befund im Prodromalstadium, Ersterkrankten und Mehrfacherkrankten (Velakoulis 2006) nachweisen lasst, Atiologie Pathogenese Veranderung unklar. Das Manuskript tragt verschiedene Befunde aus unserer Arbeitsgruppe zusammen, verschiedenen Aspekte Pathophysiologie hippokampaler beleuchten.
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