Beta-chitosan extracted from Loligo Japonica for a potential use to inhibit Newcastle disease.
作者： Xiaofei He , Ronge Xing , Kecheng Li , Yukun Qin , Ping Zou
DOI: 10.1016/J.IJBIOMAC.2015.10.059
关键词:
摘要: Beta-chitosan has a parallel structure, which differs from alpha-chitosan's antiparallel structure while producing different properties and difficulties. In this paper, we prepared the beta-chitosan through acid alkali methods resultant material was characterized by elemental analysis, FT-IR, HPLC, XRD, NMR AFS. To increase solubility biological activity of beta-chitosan, degraded it microwave-assisted process. After characterization, determined that chitosan had not changed its configuration during reaction with H2O2 under microwave irradiation. The inhibitory for Newcastle disease revealed hemagglutination test RT-PCR. yield approximately 30%, molecular weight can be to 1000 10,000g/mol. Moreover, β-chitosan higher antiviral activity, reducing titre zero, compared alpha-chitosan. Therefore, good development prospects veterinary drugs disease.
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