La(III) complex involving the O,N-donor environment of quinazoline-4(3H)-one Schiff’s base and their antimicrobial attributes against methicillin-resistant Staphylococcus aureus (MRSA)

作者: K. Siddappa , Sunilkumar B. Mane , Deene Manikprabhu

DOI: 10.1016/J.SAA.2014.03.115

关键词:

摘要: The incidence of methicillin-resistant Staphylococcus aureus increased during the past few decades, so there is an urgent need new antimicrobial agents if public health concerned. Though Schiff's bases and La(III) complex have enormous biological activity, but less attention was given in their synthesis. In present investigation, we synthesized a (E)-3-((2-hydroxynaphthalen-1-yl) methyleneamino)-2-methylquinazoline-4(3H)-one HNMAMQ base by condensation 3-(2-aminophenyl) quinazolin-2-methyl-4(3H)-one 2-hydroxy-1-naphthaldehyde. its were characterized elemental analyses, IR, NMR, mass spectra, thermal studies. newly evaluated for activity against isolated from Gulbarga region India. showed good thus represents potential drug choice.

参考文章(25)
F. Fairbrother, A text-book of quantitative inorganic analysis Journal of Inorganic and Nuclear Chemistry. ,vol. 25, pp. 745- ,(1963) , 10.1016/0022-1902(63)80176-1
Nallasamy Dharmaraj, Periasamy Viswanathamurthi, Karuppannan Natarajan, Ruthenium(II) complexes containing bidentate Schiff bases and their antifungal activity Transition Metal Chemistry. ,vol. 26, pp. 105- 109 ,(2001) , 10.1023/A:1007132408648
Athanassios Panagiotopoulos, Theodoros F. Zafiropoulos, Spyros P. Perlepes, Evangelos Bakalbassis, Isabelle Masson-Ramade, Olivier Kahn, Aris Terzis, Catherine P. Raptopoulou, MOLECULAR STRUCTURE AND MAGNETIC PROPERTIES OF ACETATO-BRIDGED LANTHANIDE(III) DIMERS Inorganic Chemistry. ,vol. 34, pp. 4918- 4920 ,(1995) , 10.1021/IC00123A029
Aida L. El-Ansary, Nora S. Abdel-Kader, Synthesis, Characterization of La(III), Nd(III), and Er(III) Complexes with Schiff Bases Derived from Benzopyran-4-one and Thier Fluorescence Study International Journal of Inorganic Chemistry. ,vol. 2012, pp. 1- 13 ,(2012) , 10.1155/2012/901415
S. Aime, S. Geninatti Crich, E. Gianolio, G.B. Giovenzana, L. Tei, E. Terreno, High sensitivity lanthanide(III) based probes for MR-medical imaging Coordination Chemistry Reviews. ,vol. 250, pp. 1562- 1579 ,(2006) , 10.1016/J.CCR.2006.03.015
Youxuan Zheng, Lianshe Fu, Yonghui Zhou, Jiangbo Yu, Yingning Yu, Shubin Wang, Hongjie Zhang, Electroluminescence based on a β-diketonate ternary samarium complex Journal of Materials Chemistry. ,vol. 12, pp. 919- 923 ,(2002) , 10.1039/B110373C
Sabrina Belaid, Anne Landreau, Safia Djebbar, Ouassini Benali-Baitich, Gilles Bouet, Jean-Philippe Bouchara, Synthesis, characterization and antifungal activity of a series of manganese(II) and copper(II) complexes with ligands derived from reduced N,N′-O-phenylenebis(salicylideneimine) Journal of Inorganic Biochemistry. ,vol. 102, pp. 63- 69 ,(2008) , 10.1016/J.JINORGBIO.2007.07.001