作者: K. Siddappa , Sunilkumar B. Mane , Deene Manikprabhu
DOI: 10.1016/J.SAA.2014.03.115
关键词:
摘要: The incidence of methicillin-resistant Staphylococcus aureus increased during the past few decades, so there is an urgent need new antimicrobial agents if public health concerned. Though Schiff's bases and La(III) complex have enormous biological activity, but less attention was given in their synthesis. In present investigation, we synthesized a (E)-3-((2-hydroxynaphthalen-1-yl) methyleneamino)-2-methylquinazoline-4(3H)-one HNMAMQ base by condensation 3-(2-aminophenyl) quinazolin-2-methyl-4(3H)-one 2-hydroxy-1-naphthaldehyde. its were characterized elemental analyses, IR, NMR, mass spectra, thermal studies. newly evaluated for activity against isolated from Gulbarga region India. showed good thus represents potential drug choice.