Modulation of the sensitivity of tumor cells to chemotherapeutics

作者: Julian A. Kim , Pierre L. Triozzi

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摘要: Disclosed is a method for improving the treatment of cancer patient which undergoing (adjuvant) chemotherapy. Prior to or concomitant with receiving adjuvant chemotherapy, administered mitogenically stimulated lymph node lymphocytes supernatant therefrom. The are excised enriched in tumor reactive cells, such as CD4+ cells. Radiolabeled locators (e.g., antibodies) can be used along portable radiation detector intraoperatively determine nodes bear cells then subjected mitogenic stimulation their expansion and administration patient.

参考文章(10)
John W. F. Goers, Chyi Lee, Richard C. Siegel, Thomas J. McKearn, John D. Rodwell, Vernon L. Alvarez, Antibody-metal ion complexes ,(1985)
Edward W Martin, Marlin O Thurston, Method for locating, differentiating, and removing neoplasms International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. ,vol. 16, ,(1986) , 10.1016/0883-2897(89)90021-4
Philip E. Thorpe, Francis J. Burrows, Methods and compositions for targeting the vasculature of solid tumors Official Gazette of the United States Patent and Trademark Office Patents. ,(1993)
Alan Epstein, Clive Taylor, Detection of necrotic malignant tissue and associated therapy International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. ,vol. 17, ,(1999) , 10.1016/0883-2897(90)90160-3
Lorne J. Brandes, Treatment method for cancer ,(1995)