Methods and reagents for profiling quantities of nucleic acids

作者: Jeffrey Sampson , Mel Kronick , Joel Myerson , Anya Tsalenko , Zohar Yakhini

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摘要: Methods and reagents are disclosed for quantitatively analyzing a set of target nucleic acid sequences. In the method unique oligonucleotide probe precursors is hybridized to sequences produce hybrids. The hybrids processed alter mass each in sequence-mediated reaction products, which has that not result presence tag product. processing may involve polymerase extension or ligation. products analyzed by means spectrometry results related amount set. Kits carrying out above methods also disclosed.

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