Challenges of Antibacterial Discovery

作者: L. L. Silver

DOI: 10.1128/CMR.00030-10

关键词:

摘要: … The challenges to antibacterial discovery have kept the output of novel antibacterial drug … to the discovery of novel small-molecule antibacterials rather than on the commercial and …

参考文章(399)
Sarah Dubrac, Tarek Msadek, Tearing down the wall: peptidoglycan metabolism and the WalK/WalR (YycG/YycF) essential two-component system. Advances in Experimental Medicine and Biology. ,vol. 631, pp. 214- 228 ,(2008) , 10.1007/978-0-387-78885-2_15
G. Segre, E. Bianchi, A. Cataldi, G. Zannini, Pharmacokinetic profile of fosfomycin trometamol (Monuril). European Urology. ,vol. 13, pp. 56- 63 ,(1987) , 10.1159/000472864
Miha Kotnik, Petra Stefanic Anderluh, Andrej Prezelj, Development of novel inhibitors targeting intracellular steps of peptidoglycan biosynthesis. Current Pharmaceutical Design. ,vol. 13, pp. 2283- 2309 ,(2007) , 10.2174/138161207781368828
Rajesh Pahwa, Steven Wilkinson Sf, Kelly Lyons, William C. Koller, Mechanism of Action Demos Medical Publishing. ,(2002)
Herve Bercovier, Orna Kafri, Shlomo Sela, Mycobacteria possess a surprisingly small number of ribosomal RNA genes in relation to the size of their genome. Biochemical and Biophysical Research Communications. ,vol. 136, pp. 1136- 1141 ,(1986) , 10.1016/0006-291X(86)90452-3
Norman J. Oppenheimer, Thomas L. James, Structure and mechanism Academic Press. ,(1989)
Bacterial signal transduction : networks and drug targets Springer Science+Business Media , Landes Bioscience. ,(2008) , 10.1007/978-0-387-78885-2
Bruno Périchon, Patrice Courvalin, Glycopeptide-Resistance in Enterococci The Journal of the Japanese Association for Infectious Diseases. ,vol. 74, pp. 229- 240 ,(2009) , 10.1007/978-1-59745-180-2_20