Metastases to the breast from nonbreast solid neoplasms: presentation and determinants of survival.

摘要: BACKGROUND. Metastasis to the breast is rare, but it must be considered in differential diagnosis of a mass. The purpose this study was identify clinical characteristics and outcomes associated with entity determinants survival. METHODS. Between 1983 1998, 169 patients were confirmed by pathology have metastasis from nonbreast solid organ primary tumors at University Texas M. D. Anderson Cancer Center. Medical records retrospectively reviewed for clinicopathological characteristics. Survival determined Kaplan-Meier analysis. RESULTS. The median age 51 years (range, 13–85). One hundred forty-nine (88.2%) had prior history cancer. Ninety-one (53.9%) presented additional systemic metastases. most common histology identified melanoma (65 patients, 38.5%). In (77%), initially made through physical examination. survival time diagnosed 10 months 0.4–192.7). On univariate analysis, significantly better observed who no evidence other disease (P = .0036), neuroendocrine .023), underwent surgical resection metastases .0001). multivariate did not surgery 88% more likely die than those < 0.001). CONCLUSIONS. Expected poor, therefore, local therapy should tailored each individual. association between overall further investigated. 2007; 110:731–7. © 2007 American Society.