Correction of malnutrition and maldigestion with enzyme supplementation in patients with surgical suppression of exocrine pancreatic function.

摘要: We studied the occurrence and extent of malnutrition maldigestion in 13 patients who underwent pancreatoduodenectomy (PD) injection Neoprene (polychloroprene) (NI) into duct Wirsung, which results sclerosis hte acinar pancreatic tissue, but spares endocrine function. At discharge, under took an enzyme supplementation regimen with pancreatin (18, 00 United States Pharmacopoeia units lipase per meal). Patients were rehospitalized 24.9 months after PD plus NI to undergo nutritional metabolic evaluation (hospital control). Nutritional status was evaluated by measuring serum albumin level, total iron binding capacity lymphocyte count. Digestive function assessed D-xylose tolerance test determination fecal fat excretion. then discharged pancrelipase, enteric-coated microspheres (ECM) (16,050 Malnutrition, defined as at least two abnormal parameters, observed six hospital control. After on pancrelipase ECM, re-evaluated nine (three previously malnourished) all well nourished. The mean body weight 84.7 cent usual discharge raised 88.0 control (p less than 0.01) 93.7 )p 0.05) ECM. control, from normal patients, steatorrhea dropped 33.6 grams day without 15.3 ECM Steatorrhea incompletely satisfactorily corrected On therapy recover a good deal normalize biochemical indices malnutrition.