作者: Harold Varmus , Robert A. Weinberg
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摘要: During the search to find a cure for cancer great deal about rules that govern normal life has been discovered, specifically reproduction and development of cells. These revelations their contribution fight against are focus this volume. The book shows how scientists have explored questions by tracing carcinogenesis its earliest detectable, submicroscopic stages. Drawing on classic recent research findings, authors explain any one many factors (including sunlight, radiation, tobacco certain viral infections) can combine with existing predispositions radically alter genetic code, turning gene into cancer-causing one. They describe what we know mechanisms genes seem promote (oncogenes) those work prevent restrain it (tumour suppressor genes). conclude review current endeavors, looking ahead possible future breakthroughs.