Activity of Flavanones Isolated from Rhododendron hainanense against Plant Pathogenic Fungi.

作者: Ya Li , Jie Zhao , Kun Gao

DOI: 10.1177/1934578X1601100513

关键词:

摘要: In a search for naturally occurring antimicrobial compounds in medicinal plants and herbs, seven flavanones were isolated from the aerial parts of Rhododendron hainanense tested their activities against six bacteria plant pathogenic fungi. Within series tested, farrerol (1) displayed moderate antibacterial Bacillus cereus, B. subtilis, Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli Erwinia carotovora, with MICs ranging 15.6 to 125 μg/mL. Furthermore, exhibited excellent inhibitory fungi: Fusarium oxysporum f sp. niveum, Colletotrichum gloeosporioides, Penicillium italicum, Rhizoctonia solani, cubenserace Phytophthora melonis, EC50 values 9, 18, 35, 39, 46 66 μg/mL, respectively. This is first report on anti-plant fungal activities.

参考文章(9)
NOBUTOSHI TANAKA, TAKAO MURAKAMI, HIROSHI WADA, ALICIA B. GUTIERREZ, YASUHISA SAIKI, CHIUMING CHEN, Chemical and Chemotaxonomical Studies of Filices. LXI. Chemical Studies on the Constituents of Pronephrium triphyllum HOLLT. Chemical & Pharmaceutical Bulletin. ,vol. 33, pp. 5231- 5238 ,(1985) , 10.1248/CPB.33.5231
Jie Zhao, Huan-Xing Ding, Deng-Gao Zhao, Chun-Ming Wang, Kun Gao, Isolation, modification and cytotoxic evaluation of flavonoids from Rhododendron hainanense. Journal of Pharmacy and Pharmacology. ,vol. 64, pp. 1785- 1792 ,(2012) , 10.1111/J.2042-7158.2012.01560.X
Théo R. Costa, Orionalda F.L. Fernandes, Suzana C. Santos, Cecı́lia M.A. Oliveira, Luciano M. Lião, Pedro H. Ferri, José R. Paula, Heleno D. Ferreira, Beatriz H.N. Sales, Maria do Rosário R. Silva, Antifungal activity of volatile constituents of Eugenia dysenterica leaf oil. Journal of Ethnopharmacology. ,vol. 72, pp. 111- 117 ,(2000) , 10.1016/S0378-8741(00)00214-2
Tamara L. Meragelman, Kenneth D. Tucker, Thomas G. McCloud, John H. Cardellina, Robert H. Shoemaker, Antifungal flavonoids from Hildegardia barteri. Journal of Natural Products. ,vol. 68, pp. 1790- 1792 ,(2005) , 10.1021/NP0503000
Hitomi Takemura, Toshimasa Itoh, Keiko Yamamoto, Hiroyuki Sakakibara, Kayoko Shimoi, Selective inhibition of methoxyflavonoids on human CYP1B1 activity Bioorganic & Medicinal Chemistry. ,vol. 18, pp. 6310- 6315 ,(2010) , 10.1016/J.BMC.2010.07.020
Hironobu Takahashi, Sachiyo Hirata, Hiroyuki Minami, Yoshiyasu Fukuyama, Triterpene and flavanone glycoside from Rhododendron simsii. Phytochemistry. ,vol. 56, pp. 875- 879 ,(2001) , 10.1016/S0031-9422(00)00493-3
T.P. Tim Cushnie, Andrew J. Lamb, Antimicrobial activity of flavonoids International Journal of Antimicrobial Agents. ,vol. 26, pp. 343- 356 ,(2005) , 10.1016/J.IJANTIMICAG.2005.09.002
James S. McLaren, Biologically active substances from higher plants: Status and future potential Pesticide Science. ,vol. 17, pp. 559- 578 ,(1986) , 10.1002/PS.2780170514
M.V.R.K. Reddy, B.K. Srivastava, New Flavonoids from the Flowers of Amaranthus Caudatus Oriental journal of chemistry. ,vol. 10, pp. 293- 294 ,(2017)