作者: Berrylin J. Ferguson , Habib Rizk , Jeevan Ramakrishnan , Harshita Pant
DOI: 10.1007/978-3-642-11412-0_12
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摘要: Chronic rhinosinusitis (CRS) with nasal polyps (NP) represents a diverse group of potential etiologies, many which may be overlapping. The clinical symptoms NP do not differentiate between etiologies. Symptoms in patients can categorized by symptom scores from several instruments, although none are specific for and correlate the extent objective disease. Sinus CT scans variety scoring systems; however, correlation sinus findings is generally poor; most widely utilized Lund–Mackay system. endoscopically size through staging systems, demonstrate intra interrater concordance, but again without demonstrated to symptoms. Objective verification performed airway patency assessment smell testing. presence predominant inflammatory cell population into eosinophilic, neutrophilic, mixed types. Presence coexisting pathogens such as bacteria or fungus response (eosinophilic vs. noneosinophilic) further distinct categories; significance categorization this manner under investigation. Categorization severity should reflect disease state, medications required control, risks treatment untreated A system that incorporates sinonasal scores, evidence (CT endoscopic scores), known risk factors recalcitrant disease, control medical surgical over time likely accurately assess assist patient’s treatment, facilitate optimal study NP.