Prosthetic Device Infections

摘要: Fortunately, infection is a rare complication of prosthetic devices. Despite the presence infection, removal these devices not always possible or necessary. The introduction foreign material enhances pathogenicity known pathogens and increases potential less virulent microorganisms to cause damage. Thus, Staphylococcus epidermidis very common organism in patients with as compared normal healthy population. Fibronectin promotes adherence staphylococci chronically implanted An extracellular substance called “glycocalyx” has been associated coagulase-negative including S. epidermidis. A polysaccharide “adhesin” facilitates functions an antiphagocytic capsule. function polymorphonuclear leukocytes also impaired bodies. There deficient superoxide production, which leads killing microorganisms. Also, recent data suggest role for small colony variants (SCV) that may persistent recurrent infections result their capacity survive within, but lyse, whole cells. When bacteria adhere bodies, they undergo dramatic metabolic changes such slower growth, decreased metabolism, enhanced resistance antibiotics. These organisms can be difficult detect microbiology laboratory treat conventional antibiotics (1).