Optimization of Exenatide plus Detemir Treatment for Morbid Obese Patients with Insulin Dependent Diabetes Resistant to Conventional Treatment. Effect of Exenatide on Patients with Mellitus Diabetes Type 2

摘要: The purpose of this study was to analyze the effects treatment with Exenatide joint insulin detemir. carried out obese patients type 2 diabetes mellitus (DM2) and deficient control, despite intensive therapy combined oral antidiabetics. A longitudinal made 15 controlled by Endocrinology Nutrition Section Reina Sofia University Hospital, Murcia. These were treated during 3, 6 12 months. Statistically meaningful differences (p＜0.05) observed in reduction HbA1c 3 months groups (initial HbA1c: 9.55%±1.086%, weight: 119.94kg, requirement: 0.71 IU/kg/day; after months: 7.77%±1.164%, 98.13kg, 0.59 7.21%, 97.93kg, 0.55 IU/kg/day). It that association promotes an improvement several indicators such as weight, body mass index (BMI), systolic pressure (SP), diastolic (DP), triglycerides (TG), cLDL, cHDL total cholesterol (TC), resistant conventional therapy. However, these improvements statistically no significant (p＜0.05). is possible talk a cardiovascular risk factors Exenatide, being thus suitable option for kind individuals. important emphasize fact our showed bigger body-weight reductions results months, compared researches quoted.