Molecular aspects of meiotic chromosome synapsis and recombination.

摘要: Publisher Summary This chapter focuses on the mechanisms that underlie chromosome alignment, synapsis, and crossover formation from much-studied meiotic systems in which pairing leads to synapsis facilitates completion of recombination, recombination ensures segregation homologs opposite poles at meiosis I division. Although several components are important for have been studied some detail, it is unclear as how intermediates processed resolved during meiosis. Further, factors govern CO or NCO remain obscure. However, studies implicate such a decision occurs prior intermediates. These also suggest SC seems unlikely play an active role regulation frequency, was previously believed. In recent years, multistranded non-B form DNA structures attracted considerable attention, with most notable being G4 DNA.