Image-guided tumor surgery: The emerging role of nanotechnology.

作者: Nicholas E. Wojtynek , Aaron M. Mohs

DOI: 10.1002/WNAN.1624

关键词:

摘要: Surgical resection is a mainstay treatment for solid tumors. Yet, methods to distinguish malignant from healthy tissue are primarily limited tactile and visual cues as well the surgeon's experience. As result, there possibility that positive surgical margin (PSM) or presence of residual tumor left behind after may occur. It well-documented PSMs can negatively impact outcomes survival, pose an economic burden. Therefore, imaging techniques have emerged promising method decrease PSM rates. Nanoparticles (NPs) unique characteristics serve optical contrast agents during image-guided surgery (IGS). Recently, has been tremendous growth in volume types NPs used IGS, including clinical trials. Herein, we describe most recent contributions nanotechnology identification. This article categorized under: Therapeutic Approaches Drug Discovery > Nanomedicine Oncologic Disease Implantable Materials Technologies Nanoscale Tools Techniques Surgery Diagnostic vivo Nanodiagnostics Imaging.

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