Use of 2-(purin-9-yl)-tetrahydofuran-3,4-diol derivatives as adenosine a2a receptor agonists
作者： Robin Alec Fairhurst , Roger John Taylor
DOI:
关键词:
摘要: A compound of formula (I) or stereoisomers pharmaceutically acceptable salts thereof, and their preparation use as pharmaceuticals wherein R1 R2 R3, R4 W are defined herein.
google.com.au 参考文章(9)
RYUJI MARUMOTO, YOSHIO YOSHIOKA, OSAMU MIYASHITA, SHUNSUKE SHIMA, KINICHI IMAI, KATSUYOSHI KAWAZOE, MIKIO HONJO, Synthesis and coronary vasodilating activity of 2-substituted adenosines. Chemical & Pharmaceutical Bulletin. ,vol. 23, pp. 759- 774 ,(1975) , 10.1248/CPB.23.759
Mark D. Okusa, Timothy L. Macdonald, Alaa S. Awad, Joel M. Linden, Agonists of A2A adenosine receptors for treatment of diabetic nephropathy ,(2005)
Timothy Macdonald, Joel M. Linden, George A. Beller, David K. Glover, Induction of pharmacological stress with adenosine receptor agonists ,(2000)
Timothy L. Macdonald, Tom G. Obrig, Joel M. Linden, W. Michael Scheld, Jayson M. Rieger, Gail W. Sullivan, Use of a2a adenosine receptor agonists for the treatment of inflammatory diseases ,(2003)
Joel M. Linden, Kenneth Brayman, Gail W. Sullivan, Method to reduce inflammatory response in transplanted tissue ,(2004)
Venkata P Palle, Elfatih O Elzein, Scott A Gothe, Zhihe Li, Zhenhai Gao, Stephanie Meyer, Brent Blackburn, Jeff A Zablocki, None, Structure-affinity relationships of the affinity of 2-pyrazolyl adenosine analogues for the adenosine A2A receptor. Bioorganic & Medicinal Chemistry Letters. ,vol. 12, pp. 2935- 2939 ,(2002) , 10.1016/S0960-894X(02)00609-1
Venkata P. Palle, Elfatih O. Elzein, Jeffrey A. Zablocki, C-pyrazole A2A receptor agonists ,(2000)
Robin Alec Fairhurst, Roger John Taylor, Purine derivatives acting as a2a receptor agonists ,(2006)
Robin Alec Fairhurst, Roger John Taylor, Adenosine derivatives having a2a receptor activity ,(2006)