Evaluation of texture analysis for the differential diagnosis of focal nodular hyperplasia from hepatocellular adenoma on contrast-enhanced CT images.

摘要: To explore the value of CT texture analysis (CTTA) for differentiation focal nodular hyperplasia (FNH) from hepatocellular adenoma (HCA) on contrast-enhanced (CECT). This is a retrospective, IRB-approved study conducted in single institution. A search medical records between 2008 and 2017 revealed 48 patients with 70 HCA 50 62 FNH. All lesions were histologically proven available pre-operative CECT imaging. Hepatic arterial phase (HAP) portal venous (PVP) used CTTA. Textural features extracted using commercially research software (TexRAD). The differences textural parameters FNH assessed Mann–Whitney U test AUROC calculated. CTTA showing significant difference rank sum binary logistic regression analysis. p value < 0.05 was considered statistically significant. On HAP images, mean, mpp, skewness significantly higher than unfiltered images (p ≤ 0.007); SD, entropy, mpp filtered (p ≤ 0.006). PVP, different (p ≤ 0.001) while entropy kurtosis (p ≤ 0.018). multivariate indicated that medium-level coarse-level independent predictors diagnosis model based all these showed largest (0.824). Multiple explored are CECT.