Molecular cloning and mapping of a novel ADAM gene (ADAM29) to human chromosome 4.
作者： Rener Xu , Jinli Cai , Tian Xu , Weigou Zhou , Beibei Ying
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摘要: Members of the ADAM family (type I integral membrane protein with a disintegrin and metalloprotease domain) have been implicated in many important biological processes involving cell-cell cell-matrix interactions, such as fertilization myoblast fusion. We report here cDNA sequence novel human gene (ADAM29) that contains putative fusion peptide. Northern blot analysis revealed mRNA ADAM29 is highly expressed testis. By radiation hybrid panel mapping, was assigned to chromosome 4q34.2-qter.
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