The antibacterial peptide pyrrhocoricin inhibits the ATPase actions of DnaK and prevents chaperone-assisted protein folding.

作者: Goran Kragol , Sandor Lovas , Gyorgyi Varadi , Barry A. Condie , Ralf Hoffmann

DOI: 10.1021/BI002656A

关键词:

摘要: Recently, we documented that the short, proline-rich antibacterial peptides pyrrhocoricin, drosocin, and apidaecin interact with the bacterial heat shock protein DnaK, and peptide …

参考文章(6)
Gyorgyi I. Szendrei, Heinz Fabian, Henry H. Mantsch, Sandor Lovas, Olga Nyeki, Istvan Schon, Laszlo Otvos, Aspartate-Bond Isomerization Affects the Major Conformations of Synthetic Peptides European Journal of Biochemistry. ,vol. 226, pp. 917- 924 ,(1994) , 10.1111/J.1432-1033.1994.T01-1-00917.X
Boguslaw Stec, Kathleen M. Holtz, Evan R. Kantrowitz, A revised mechanism for the alkaline phosphatase reaction involving three metal ions. Journal of Molecular Biology. ,vol. 299, pp. 1303- 1311 ,(2000) , 10.1006/JMBI.2000.3799
Phippe Bulet, Laszlo Urge, Serge Ohresser, Charles Hetru, Laszlo Otvos, Enlarged Scale Chemical Synthesis and Range of Activity of Drosocin, an O‐Glycosylated Antibacterial Peptide of Drosophila FEBS Journal. ,vol. 238, pp. 64- 69 ,(1996) , 10.1111/J.1432-1033.1996.0064Q.X
Madalyn Castle, Arpi Nazarian, San San Yi, Paul Tempst, Lethal Effects of Apidaecin on Escherichia coliInvolve Sequential Molecular Interactions with Diverse Targets Journal of Biological Chemistry. ,vol. 274, pp. 32555- 32564 ,(1999) , 10.1074/JBC.274.46.32555
B.C. Freeman, M.P. Myers, R. Schumacher, R.I. Morimoto, Identification of a regulatory motif in Hsp70 that affects ATPase activity, substrate binding and interaction with HDJ-1. The EMBO Journal. ,vol. 14, pp. 2281- 2292 ,(1995) , 10.1002/J.1460-2075.1995.TB07222.X