The Consumption of Lycopene and Tomato-Based Food Products Is Not Associated with the Risk of Type 2 Diabetes in Women

摘要: Lycopene is a major carotenoid with potent antioxidant properties that may provide protection against the development of type 2 diabetes mellitus (DM). In this study we examined association between baseline dietary intakes lycopene, lycopene-containing foods, and subsequent DM in large prospective cohort study. We analyzed total 35,783 women from United States, aged > or =45 y free self-reported cardiovascular disease, cancer, at baseline. Intakes lycopene individual tomato-based food products were assessed by 131-item-validated semiquantitative food-frequency questionnaire. During median follow-up 10.2 y, 1544 cases incident documented. After adjusting for age, energy intake, randomized treatment assignment, body mass index, other known risk factors, multivariate-adjusted relative risks 95% CI across increasing quintiles 1.00 (baseline), 1.10 (0.94-1.29), 1.07 (0.91-1.26) (P linear trend = 0.56). Compared who consumed =10 servings/wk had multivariate (95% CI) 1.03 (0.88-1.20), 1.02 (0.87-1.20), 1.09 (0.89-1.33), 1.04 (0.80-1.36), respectively 0.54). The associations similar to results combination all tomato products. Our found little evidence an intake foods DM.