作者: Rene Scheenstra , Willem Jan Gerver , Roelof J Odink , Hanneke van Soest , Paul MJG Peeters
DOI: 10.1097/MPG.0B013E3181623279
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摘要: Objective: To evaluate the effect of end-stage pediatric liver disease and transplantation on growth final height. Patients Methods: We evaluated at 2 years (n = 101) 5 63) after (LTx). Twenty-three children reached Height was expressed as a standard deviation score target height (z(TH) score) each patient. Results: At first LTx, z(TH) significantly increased from -1.7 to -1.3 SD (P <0.05). Growth or Delta score, positively correlated with pretransplant retardation In comparison patients noncholestatic primary disease, cholestatic were more severely retarded before LTx -2.0 vs -1.2 SD, P <0.05) had better in (Delta +0.6 -0.1 Twelve 23 below their Conclusions: is common particularly an underlying disease. After catch-up partial prominent only who been LTx. during childhood, similar 50% reach lower than genetic potential JPGN 47.165-171, 2008.