The Rabbit Model of Asthma and the Late Asthmatic Response

作者: Caroline M. Herd , Clive P. Page

DOI: 10.1007/978-3-0348-9000-7_7

关键词:

摘要: The prevalence and incidence of atopy asthma is increasing in the industrialized world, particularly amongst children [1, 2]. Asthma a chronic disease characterized by variety features including reversible airway obstruction, increased responsiveness to various stimuli, inflammation. Various animal models (see accompanying chapters) have been established mimic study specific aspects human asthmatic response. This chapter discusses similarities between allergic rabbit model condition hence value for investigation pathophysiology development novel therapeutic agents.

参考文章(114)
NM Roberts, M McCusker, KF Chung, PJ Barnes, Effect of a PAF antagonist, BN52063, on PAF-induced bronchoconstriction in normal subjects. British Journal of Clinical Pharmacology. ,vol. 26, pp. 65- 72 ,(1988) , 10.1111/J.1365-2125.1988.TB03365.X
Peter J. Barnes, Maria G. Belvisi, Duncan F. Rogers, Modulation of neurogenic inflammation: novel approaches to inflammatory disease Trends in Pharmacological Sciences. ,vol. 11, pp. 185- 189 ,(1990) , 10.1016/0165-6147(90)90112-L
L A Laitinen, A Laitinen, P A Panula, M Partanen, K Tervo, T Tervo, Immunohistochemical demonstration of substance P in the lower respiratory tract of the rabbit and not of man. Thorax. ,vol. 38, pp. 531- 536 ,(1983) , 10.1136/THX.38.7.531
B. R. Wiggs, C. Bosken, P. D. Paré, A. James, J. C. Hogg, A Model of Airway Narrowing in Asthma and in Chronic Obstructive Pulmonary Disease American Review of Respiratory Disease. ,vol. 145, pp. 1251- 1258 ,(1992) , 10.1164/AJRCCM/145.6.1251
Jonathan P Arm, Bernd W Spur, Tak H Lee, None, The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects. The Journal of Allergy and Clinical Immunology. ,vol. 82, pp. 654- 660 ,(1988) , 10.1016/0091-6749(88)90979-7
Caroline M. Herd, Donna Donigi-Gale, T. Scott Shoupe, Stephen A. Kilfeather, Sade A. Okiji, Clive P. Page, Effect of PF 10040 on PAF-induced airway responses in neonatally immunized rabbits. British Journal of Pharmacology. ,vol. 111, pp. 7- 12 ,(1994) , 10.1111/J.1476-5381.1994.TB14016.X
Caroline M. Herd, Donna Donigi-Gale, T. Scott Shoupe, Clive P. Page, Effect of a 5-lipoxygenase inhibitor and leukotriene antagonist (PF 5901) on PAF-induced airway responses in neonatally immunized rabbits. British Journal of Pharmacology. ,vol. 107, pp. 1108- 1115 ,(1992) , 10.1111/J.1476-5381.1992.TB13415.X
D. W. COCKCROFT, R. E. RUFFIN, J. DOLOVICH, F. E. HARGREAVE, Allergen‐induced increase in non‐allergic bronchial reactivity Clinical & Experimental Allergy. ,vol. 7, pp. 503- 513 ,(1977) , 10.1111/J.1365-2222.1977.TB01481.X
Suzanne Ollerenshaw, Deborah Jarvis, Ann Woolcock, Colin Sullivan, Tethys Scheibner, Absence of immunoreactive vasoactive intestinal polypeptide in tissue from the lungs of patients with asthma. The New England Journal of Medicine. ,vol. 320, pp. 1244- 1248 ,(1989) , 10.1056/NEJM198905113201904
M.J. Cushley, A.E. Tattersfield, S.T. Holgate, Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects British Journal of Clinical Pharmacology. ,vol. 58, pp. S751- S755 ,(2004) , 10.1111/J.1365-2125.2004.02285.X