Study of Nano Hydroxyapatite/ Poly(Lactic Acid)-Polycaprolactone Nanofiber Composite Scaffolds
作者： Guojie Xu , Fei Luo , Yan Liu , Shunyu Chen , Xiufeng Xiao
关键词:
摘要: At present, tissue engineering scaffolds in the process of clinical medicine plays an irreplaceable important role. Based on in-situ precipitation combined with frozen extraction, good n-HA dispersion and three-dimensional (3D) structure n-HA/PLLA-PCL composite nanofibrous were prepared. The effects proportion polymer, gel temperature amount calcium phosphate solution morphology investigated. From experimental results,it can be concluded that scaffolds’ have changed while proportions polymer are different, more PCL, fiber diameter increases. low (-10°C or lower), could able to get relatively uniform nano network structure, at high (0°C higher), nanofibers tend flake growth, support is compact. Also, adding (NH4)2HPO4 solution, nanometer increases, however, degree uniformity decreases. Keywordshydroxyapatite scaffold; nanofibers; thermal induced phase separation technique; precipitation; extraction
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