The effect of continuous positive airway pressure treatment on physical activity in patients with obstructive sleep apnoea: A randomised controlled trial.

摘要: BACKGROUND: Continuous positive airway pressure (CPAP) improves daytime sleepiness in patients with obstructive sleep apnoea (OSA). The effect of CPAP on physical activity is unclear. We hypothesized that would increase after treatment. METHODS: A double blind, parallel, randomised, controlled trial using therapeutic and placebo was performed men newly diagnosed OSA (more than 10>4% SaO(2) dips/hour Epworth Sleepiness Score [ESS] 9). Activity measured by wrist actigraphy before three months therapy. RESULTS: Thirty-six completed 1 week continuous (n=16) or (n=20). two groups were well-matched at baseline, no significant differences mean age, body mass index, ESS dips/hour. Mean (SD) modified maintenance wakefulness test (OSLER) improved significantly CPAP. change the group -6.1 (4.4), compared to placebo, -2.8 (5.0); difference between p=0.04; OSLER (minutes), +10.4 (14.4), -5.0 (12.0), p=0.003. There hourly levels for seven days baseline; did not either [daytime (arbitrary units): -13.9 (93.1) vs. +8.3 (62.9), p=0.4]. correlation use. CONCLUSION: does OSA, despite improvements sleepiness. reasons this are clear, but may be due longstanding, habitual patterns activity.