Incidence of cervical lymph node metastasis and its association with outcomes in patients with adenoid cystic carcinoma. An international collaborative study

作者: Moran Amit , Yoav Binenbaum , Kanika Sharma , Naomi Ramer , Ilana Ramer

DOI: 10.1002/HED.23711

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摘要: Background The patterns of regional metastasis in adenoid cystic carcinoma (ACC) the head and neck its association with outcome is not established. Methods We conducted a retrospective multicentered multivariate analysis 270 patients who underwent dissection. Results The incidence rate metastases was 29%. The observed oral cavity 37%, major salivary glands 19% (p = .001). occult nodal 17%. Overall 5-year survival rates were 44% undergoing therapeutic dissections, 65% 73% among those elective without metastases, respectively .017). Multivariate revealed that primary site, classification, margin status independent predictors survival. Conclusion Our findings support consideration treatment ACC cavity. © 2014 Wiley Periodicals, Inc. Head Neck 37: 1032–1037, 2015

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