On the development of new biocatalytic processes for practical pharmaceutical synthesis.

作者: Gjalt W Huisman , Steven J Collier

DOI: 10.1016/J.CBPA.2013.01.017

关键词:

摘要: … the substrate range of the Lactobacillus kefir KRED and subsequently enabling scalable processes … that could be readily telescoped to the nitrile upon completion of the biocatalytic step. …

参考文章(46)
Caroline Susan Lee, Richard Anthony Wisdom, Robert Christopher Chiroscience Limited Brown, Microorganism, lactamase enzyme obtained therefrom, and their use ,(1997)
Joly Sukumaran, Lynne Gilson, Robert John Wilson, Wan Lin Yeo, Steven James Collier, Junye Xu, Oscar Alvizo, Ee Ling Teo, Variant LOVD polypeptides and their uses ,(2010)
Timothy James Norman Watson, Padraig Mary O'neill, David William Bauer, Shanghui Hu, Process for preparing chiral compounds ,(2008)
Alexander Varvak, Kelvin Wong, William Greenberg, Mark J. Burk, Chemoenzymatic methods for the synthesis of statins and statin intermediates ,(2003)
Werner Hummel, Enzyme-catalyzed synthesis of optically pure R(+)-phenylethanol Biotechnology Letters. ,vol. 12, pp. 403- 408 ,(1990) , 10.1007/BF01024393
Steven K. Ma, John Gruber, Chris Davis, Lisa Newman, David Gray, Alica Wang, John Grate, Gjalt W. Huisman, Roger A. Sheldon, A green-by-design biocatalytic process for atorvastatin intermediate Green Chemistry. ,vol. 12, pp. 81- 86 ,(2010) , 10.1039/B919115C
U. T. Bornscheuer, G. W. Huisman, R. J. Kazlauskas, S. Lutz, J. C. Moore, K. Robins, Engineering the third wave of biocatalysis Nature. ,vol. 485, pp. 185- 194 ,(2012) , 10.1038/NATURE11117
Jong-Shik Shin, Byung-Gee Kim, Transaminase-catalyzed asymmetric synthesis of l -2-aminobutyric acid from achiral reactants Biotechnology Letters. ,vol. 31, pp. 1595- 1599 ,(2009) , 10.1007/S10529-009-0057-7
C. K. Savile, J. M. Janey, E. C. Mundorff, J. C. Moore, S. Tam, W. R. Jarvis, J. C. Colbeck, A. Krebber, F. J. Fleitz, J. Brands, P. N. Devine, G. W. Huisman, G. J. Hughes, Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture Science. ,vol. 329, pp. 305- 309 ,(2010) , 10.1126/SCIENCE.1188934
Carlos A. Martinez, Shanghui Hu, Yves Dumond, Junhua Tao, Patrick Kelleher, Liam Tully, Development of a Chemoenzymatic Manufacturing Process for Pregabalin Organic Process Research & Development. ,vol. 12, pp. 392- 398 ,(2008) , 10.1021/OP7002248