Breast cancer patient's cell-mediated immune response to thomsen-friedenreich (T) antigen

作者: Georg F. Springer , M. Satya Murthy , Parimal R. Desai , Edward F. Scanlon

DOI: 10.1002/1097-0142(19800615)45:12<2949::AID-CNCR2820451210>3.0.CO;2-L

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摘要: Thomsen-Friedenreich (T) antigenic specificity as determined with human serum anti-T was found in reactive form breast adenocarcinomata but not healthy and generally benign tissues. T-antigenic demonstrable all metastatic carcinoma lesions. T also present adeno- squamous cell carcinomata from other organs; it the four melanomata, one glioblastoma, seven non-breast tumors. Breast patients people showed cellular immunity to antigen vivo vitro. Most striking delayed-type cutaneous hypersensitivity reaction that positive over 85% of ductal tested, negative 94% disease patients, presumably individuals investigated. is readily available red blood cells uncontaminated form, free HL-A Australia antigens.

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