作者: Ai-hua Zhang , Shi Qiu , Hong-ying Xu , Hui Sun , Xi-jun Wang
DOI: 10.1016/J.CCA.2013.11.037
关键词:
摘要: Characterization of metabolic changes is key to early detection, treatment, and understanding molecular mechanisms diabetes. Diabetes represents one the most important global health problems. Approximately 90% diabetics have type 2 Identification effective screening markers critical for treatment intervention that can delay and/or prevent complications associated with this chronic disease. Fortunately, metabolomics has introduced new insights into pathology diabetes as well predict disease onset revealed biomarkers improve diagnostics in a range diseases. Small-molecule metabolites an role biological systems represent attractive candidates understand T2D phenotypes. Characteristic patterns be broaden our disorder. This technique-driven review aims demystify T2D, provide updates on applications addressing focus based biomarker discovery.