Incidence of and Risk Factors for Infection or Colonization of Vancomycin-Resistant Enterococci in Patients in the Intensive Care Unit

摘要: The prevalence of vancomycin-resistant enterococci (VRE) colonization or infection in the hospital setting has increased globally. Many previous studies had analysed risk factors for acquiring VRE, based on cross-sectional prevalent cases. However, actual incidence and VRE remain unclear. present study was conducted order to clarify intensive care unit (ICU). From 1st April 2008 31st March 2009, all patients admitted a surgical ICU (SICU) were put active surveillance VRE. cultures, obtained by rectal swab, taken admission, weekly while staying SICU, discharge from SICU. A total 871 screened. Among them, 34 found carry before their admission 47 acquired during stay five whom developed infections. newly 21.9 per 1000 patient-days (95% confidence interval [CI], 16.4–29.1). Using multivariate analysis logistic regression, we that length an independent factor new acquisition In contrast, with prior exposure first-generation cephalosporin significantly less likely acquire Strategies reduce duration prudent usage broad-spectrum antibiotics are keys controlling transmission.