Isolation and structure of a human fibroblast interferon gene.
作者： Rik Derynck , Jean Content , Erik DeClercq , Guido Volckaert , Jan Tavernier
DOI: 10.1038/285542A0
关键词:
摘要: Chimaeric plasmids containing double-stranded cDNA copies of mRNA induced in human fibroblasts by poly I · C were screened an RNA selection method. A series clones to which fibroblast interferon selectively hybridized was identified. From the nucleotide sequence gene, complete amino acid deduced. The protein is 166 acids long and preceded a 21-amino signal sequence.
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