Cross-National Diagnosis of Schizophrenia in Twins

摘要: An international panel of seven diagnosticians from Japan, Sweden, the United Kingdom, and States blindly diagnosed histories 114 twins in Maudsley schizophrenic twin series. The middle-of-the-road consensus diagnosis schizophrenia was easily reached. Besides being more reliable, it gave better monozygotic to dizygotic (MZ:DZ) discrimination than attempts apply broader or narrower diagnostic criteria. A similar standard applied other recent studies secured reasonable agreement, pooled MZ concordance rate 46%, higher sometimes reported. study vindicates both its substantial heritability.