作者: P. HEMMERICH , W.-R. KNAPPE
DOI: 10.1016/B978-0-08-016874-6.50048-5
关键词:
摘要: Publisher Summary This chapter focuses on model studies and mechanisms of flavin-dependent substrate dehydrogenation. A carbanion affinity the flavin nucleus its enhancement by protein would run parallel to well-known for soft anions like sulfite. The disproportionation as depending pH, half-reduced 1-alkylated is compared with analogous 5-alkylated system. At pH < 2, both systems are fully comproportionated yielding semiquinone cations quantitatively. available body information irreversible reductions flavoquinone leads conclusion that XH-activation means (X-)-transfer C(4a)=N(5) azomethine group flavoquinone. This subgroup should therefore be free prosthetic in XH-activating flavoproteins, which again consistent above-mentioned arguments H-bridged N(1).