A prolonged QRS duration on surface electrocardiogram is a specific indicator of left ventricular dysfunction

摘要: Abstract Objective. We sought to determine whether a prolonged QRS interval duration is associated with decreased left ventricular (LV) systolic function. Background. The 12-lead electrocardiogram (ECG) routine test for suspected cardiac disease. Although several scoring systems have been devised estimate LV function, no studies examined the direct relationship between alone and Methods. analyzed standard surface ECG of 270 consecutive patients, referred radionuclide ventriculography. Patients (n = 44) bundle branch blocks, atrial flutter or fibrillation, pacemaker rhythm, recent myocardial infarction bypass surgery, patients on antiarrhythmic drugs were excluded. In remaining 226), we correlated resting ECG, ejection fraction (EF), end-systolic end-diastolic counts (ESC EDC, respectively; volume indices), as obtained by angiography. used multivariate analysis identify independent predictors reduced function entering duration, previously described R-wave score clinical variables in our model. Results. abnormal EF group was significantly longer than normal (0.102 vs. 0.091 s, p 0.10 s highly specific (83.6%), but modestly sensitive (43.8%), prediction EF. Furthermore, an predicted incrementally increased specificity (83.6% 99.3%) corresponding decrease sensitivity (43.8% 13.8%) each 0.01-s increase definition (from >0.10 >0.12 s). Accordingly, positive likelihood ratio from 2.67 19.7 s. analysis, low only Conclusions. Prolonged (>0.10 s) specific, relatively insensitive indicator Further prolongation had higher predicting