Immunohistochemical study of osteopontin in oral squamous cell carcinoma allied to fractal dimension.

摘要: The aim of the study was to consider a possible correlation between intensity expression osteopontin and grading established by pathologist. Furthermore, investigated increase fractal dimension in order use this marker as an early reliable diagnostic tool for degree cell transformation oral squamous carcinoma. Ten histologically healthy samples sixty-four primary carcinomas specimens were analysed single Immunohistochemical analysis Fulgen stain performed evaluate dimension. Data obtained presented mean standard deviation processed statistical analysis. Ostepontin revealed significance groups (P less than 0.001). Fractal carcinoma vs controls statistically significant differences value compared, using two-dimensional scatter. relevant G3 group. results demonstrated growths nuclear abnormality measured These support hypothesis that level might be used evaluation differentiation. Osteopontin could histological predictability diagnosis, choices treatment procedure long-term prognosis.