作者: Leila M Marchi Alves , Luiz RO Tosi , José Antunes-Rodrigues , Evelin C Cárnio , None
DOI: 10.1016/J.REGPEP.2004.02.023
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摘要: Abstract Long-term nitric oxide (NO) blockade is known to induce a severe and progressive hypertension. The influence of the salt-intake on atrial natriuretic peptide (ANP) system in this hypertension model unknown. aim study was evaluate ANP plasma levels, content mRNA atria male Wistar rats chronically treated with oral N ω -nitro- l -arginine methyl ester ( -NAME) after 4 weeks high-salt diet. diet induced an increase P