Thiazides and Bone Mineral Density in Elderly Men and Women

摘要: The relation of bone mineral density the ultradistal radius, midshaft hip, and lumbar spine to thiazide use were examined in a community-based sample 1,696 white men women aged 44-98 years. Male users had higher age-adjusted levels only at radius (p < 0.05). Among women, significantly all four sites 0.05), both before after controlling for effects age, body mass index, smoking, estrogen use. association was explained by current use; no significant found between past or duration levels. Results similar when hypertensive excluded from analyses, suggesting effect drug-related not due hypertension some other factor related hypertension. At sites, highest seen currently using thiazide. Overall, these findings suggest that thiazides may be useful prevention osteoporosis postmenopausal women.