Physical Activity and Risk of Alcohol Use Disorders: Results from a Prospective Cohort Study

摘要: Aims: To examine the effect of physical activity on risk developing alcohol use disorders in a large prospective cohort study with focus leisure-time activity. Methods: Data came from four examinations Copenhagen City Heart Study (CCHS), performed 1976–1978, 1981–1983, 1991–1994 and 2001–2003. Information (classified as Moderate/high, low or sedentary) covariates was obtained through self-administered questionnaires, information Danish Hospital Discharge Register, Psychiatric Central Research Register Winalco database. In total, 18,359 people participated study, mean follow-up time 20.9 years. Cox proportional hazards model delayed entry used. Models were adjusted for available (age, smoking habits, intake, education, income cohabitation status) including updated time-dependent variables whenever possible. Results: A moderate/high associated almost half disorder compared sedentary This translates into 1.5- to 2-fold increased (Hazard ratios men 1.64; 95% CI 1.29–2.10 women 1.45; 1.01–2.09) individuals activity, moderate high level. However, when stratifying by presence other psychiatric disorders, no association observed comorbidity. Residual confounding may have been present this especially according rough measures education. Conclusions: both women, being leisure factor an disorder.