Role of mesenchymal stem cells, their derived factors, and extracellular vesicles in liver failure
作者： Jie Wang , Panpan Cen , Jiajia Chen , Linxiao Fan , Jun Li
DOI: 10.1186/S13287-017-0576-4
关键词:
摘要: Liver failure is a severe clinical syndrome with poor prognosis. Mesenchymal stem cell (MSC) transplantation has emerged as new intervention in treating liver failure. It conventionally recognized that MSCs exert their therapeutic effect mainly through transdifferentiation. Recently, published articles have shown work by secreting trophic and immunomodulatory factors well extracellular vesicles (EVs) before In particular,MSC-derived EVs similar curative effects MSCs. Here we review the role of MSCs as derived discuss use MSC-derived instead intact
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