Hotair mediates hepatocarcinogenesis through suppressing miRNA-218 expression and activating P14 and P16 signaling
作者： Wei-Ming Fu , Xiao Zhu , Wei-Mao Wang , Ying-Fei Lu , Bao-Guang Hu
DOI: 10.1016/J.JHEP.2015.05.016
关键词:
摘要: Background & Aims Long non-coding RNA Hotair has been considered as a pro-oncogene in multiple cancers. Although there is emerging evidence that reveals its biological function …
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Xinqi He, Yujuan Dong, Chung Wah Wu, Zengren Zhao, Simon S M Ng, Francis K L Chan, Joseph J Y Sung, Jun Yu, MicroRNA-218 Inhibits Cell Cycle Progression and Promotes Apoptosis in Colon Cancer by Downregulating BMI1 Polycomb Ring Finger Oncogene Molecular Medicine. ,vol. 18, pp. 1491- 1498 ,(2012) , 10.2119/MOLMED.2012.00304
Jacqueline J. L. Jacobs, Karin Kieboom, Silvia Marino, Ronald A DePinho, Maarten van Lohuizen, The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus Nature. ,vol. 397, pp. 164- 168 ,(1999) , 10.1038/16476
Libing Song, Quan Huang, Kun Chen, Liping Liu, Chuyong Lin, Ting Dai, Chunping Yu, Zhiqiang Wu, Jun Li, miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β Biochemical and Biophysical Research Communications. ,vol. 402, pp. 135- 140 ,(2010) , 10.1016/J.BBRC.2010.10.003
Long Huang, Ling-Min Liao, An-Wen Liu, Jian-Bing Wu, Xiao-Ling Cheng, Jia-Xin Lin, Min Zheng, Overexpression of long noncoding RNA HOTAIR predicts a poor prognosis in patients with cervical cancer Archives of Gynecology and Obstetrics. ,vol. 290, pp. 717- 723 ,(2014) , 10.1007/S00404-014-3236-2
Hiroyuki Endo, Takeharu Shiroki, Takayuki Nakagawa, Misa Yokoyama, Keiichi Tamai, Hideaki Yamanami, Tsuneaki Fujiya, Ikuro Sato, Kazunori Yamaguchi, Nobuyuki Tanaka, Katsunori Iijima, Tooru Shimosegawa, Kazuo Sugamura, Kennichi Satoh, Enhanced Expression of Long Non-Coding RNA HOTAIR Is Associated with the Development of Gastric Cancer PLoS ONE. ,vol. 8, pp. e77070- ,(2013) , 10.1371/JOURNAL.PONE.0077070
James V. Tricoli, James W. Jacobson, MicroRNA: Potential for Cancer Detection, Diagnosis, and Prognosis. Cancer Research. ,vol. 67, pp. 4553- 4555 ,(2007) , 10.1158/0008-5472.CAN-07-0563
Tony Gutschner, Sven Diederichs, The hallmarks of cancer: a long non-coding RNA point of view. RNA Biology. ,vol. 9, pp. 703- 719 ,(2012) , 10.4161/RNA.20481
Yangchao Chen, Marie C. Lin, Hong Yao, Hua Wang, Ai-Qun Zhang, Jun Yu, Chee-kin Hui, George K. Lau, Ming-liang He, Joseph Sung, Hsiang-fu Kung, Lentivirus‐mediated RNA interference targeting enhancer of zeste homolog 2 inhibits hepatocellular carcinoma growth through down‐regulation of stathmin Hepatology. ,vol. 46, pp. 200- 208 ,(2007) , 10.1002/HEP.21668
De-Wei Wu, Ya-Wen Cheng, John Wang, Chih-Yi Chen, Huei Lee, Paxillin Predicts Survival and Relapse in Non–Small Cell Lung Cancer by MicroRNA-218 Targeting Cancer Research. ,vol. 70, pp. 10392- 10401 ,(2010) , 10.1158/0008-5472.CAN-10-2341
Chi Han Li, Ka–Fai To, Joanna Hung–Man Tong, Zhangang Xiao, Tian Xia, Paul BS Lai, Sheung Ching Chow, Yin–Xin Zhu, Stephen L Chan, Victor E Marquez, Yangchao Chen, None, Enhancer of Zeste Homolog 2 Silences MicroRNA-218 in Human Pancreatic Ductal Adenocarcinoma Cells by Inducing Formation of Heterochromatin Gastroenterology. ,vol. 144, pp. 1086- 1097 ,(2013) , 10.1053/J.GASTRO.2013.01.058