Optimization of facility location and reallocation in an industrial plant through a multi-annual framework accounting for economic and safety issues

摘要: Abstract The industrial layout traditionally has been addressed accounting for the facilities distribution and installation since first day of operation plant; this is, without considering future expansions that involve additional in years. This way, paper proposes a mathematical programming formulation optimal facility sitting reallocation an industry involving simultaneously economic safety objectives. proposed is based on multi-annual framework corresponds to multi-objective mixed integer linear problem. optimization approach was applied case study (office buildings control rooms) ethylene oxide plant. objective function involves minimization total annual cost value money through time accumulated risk over time. Results show applicability approach.