C-class oligonucleotide analogs with enhanced immunostimulatory potency
作者： Arthur M. Krieg , Eugen Uhlmann , Bernhard O. Noll , Joerg Vollmer
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摘要: The invention relates to a class of CpG immunostimulatory oligonucleotides containing motif and second which is capable forming secondary structure, including duplex higher order structures, in vitro vivo. the are useful as adjuvants vaccination. also for inducing an immune response, expression type I interferon (IFN), gamma (IFN-Ϝ), treating variety conditions, allergy, asthma, infection, cancer.
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