In vivo high resolution 3D-QCT of the human forearm

摘要: In vivo examinations of bone microarchitecture have become available recently through high resolution computed tomography (3D-QCT) and magnetic resonance imaging. The spatial the resulting images, however, is not sufficient to depict individual trabeculae in their true shape. Nevertheless, structural indices such as relative volume, trabecular number, mean thickness separation can be extracted with help a ridge detection algorithm. Precision procedure order 1%, accuracy ascertained using micro-CT based calibration. In this work we report first results time serial examinations. Eighteen healthy postmenopausal women (no HRT) were measured at months 0, 6, 12, temporal changes analyzed. Examination site was distal radius. above mentioned indices, average densities cortical shell determined. Of 18 6 showed no significant loss any kind, 5 lost primarily cancellous bone, 4 3 had substantial well bone. We conclude that even homogenous group women, there are considerable differences reason why weakend 3D-QCT allows differentiate between various types loss.