The biosynthesis of the alkaloids of stephania glabra (ROXB.) miers
作者： Dewan S. Bhakuni , Sandeep Gupta , Sudha Jain
DOI: 10.1016/S0040-4020(01)90908-1
关键词:
摘要: Tracer experiments show that the tetrahydroprotoberberines stepholidine (14), corydalmine (d15), capaurine (19) and corynoxidine (20) are stereospecifically biosynthesized from (S)-reticuline (22) whereas bisbenzylisoquinoline alkaloids cycleanine (52), N-desmethylcycleanine (51) proaporphine alkaloids. pronuciferine (27) stepharine (26) derived (R)-N-methylcoclaurine in young Stephania glabra. The quaternary protoberberine (40 to 44) of plant formed by dehydrogenation corresponding tetrahydroprotoberberines.
elsevier.com
sci-hub.se 参考文章(10)
Dewan S. Bhakuni, Sudha Jain, The biosynthesis of the alkaloids of croton sparsiflorus morong Tetrahedron. ,vol. 37, pp. 3175- 3181 ,(1981) , 10.1016/S0040-4020(01)98851-9
Dewan S. Bhakuni, Sudha Jain, Sandeep Gupta, Biosynthesis of tetrahydropalmatine and palmatine Tetrahedron. ,vol. 36, pp. 2491- 2495 ,(1980) , 10.1016/0040-4020(80)80228-6
D. S. Bhakuni, S. Gupta, The Alkaloids of Stephania glabra Journal of Natural Products. ,vol. 45, pp. 407- 411 ,(1982) , 10.1021/NP50022A007
Dewan S. Bhakuni, Virender M. Labroo, Awadhesh N. Singh, Randhir S. Kapil, Biosynthesis of the bisbenzylisoquinoline alkaloid cocsulin Journal of the Chemical Society, Perkin Transactions 1. pp. 121- 125 ,(1978) , 10.1039/P19780000121
Richard H. F. Manske, H. L. Holmes, The Alkaloids of Fumariaceous Plants. XXXIX. The Constitution of Capaurine Journal of the American Chemical Society. ,vol. 67, pp. 95- 98 ,(1945) , 10.1021/JA01217A034
M. P. Cava, K. Nomura, S. K. Talapatra, M. J. Mitchell, R. H. Schlessinger, K. T. Buck, J. L. Beal, B. Douglas, R. F. Raffauf, J. A. Weisbach, Alkaloids of Stephania glabra. Direct chemical correlation of the absolute configuration of some benzyltetrahydroisoquinoline, proaporphine, and aporphine alkaloids. New protoberberine alkaloid Journal of Organic Chemistry. ,vol. 33, pp. 2785- 2789 ,(1968) , 10.1021/JO01271A037
Raymond W. Doskotch, M. Younas Malik, Jack L. Beal, The identification of dehydrocorydalmine and a new protoberberine alkaloid, stepharanine, in Stephania glabra tubers. Journal of Organic Chemistry. ,vol. 32, pp. 3253- 3254 ,(1967) , 10.1021/JO01285A091
A. R. Battersby, B. J. T. Harper, 691. Alkaloid biosynthesis. Part I. The biosynthesis of papaverine Journal of the Chemical Society (Resumed). pp. 3526- 3533 ,(1962) , 10.1039/JR9620003526
Masao Tomita, Eiichi Fujita, Fujio Murai, Cleavage of Biscoclaurine Alkaloids by Metallic Sodium in Liquid Ammonia Yakugaku Zasshi-journal of The Pharmaceutical Society of Japan. ,vol. 71, pp. 301- 302 ,(1951) , 10.1248/YAKUSHI1947.71.4_301
A.R. Skerl, E.G. Gros, Biosynthesis of palmatine in Fagara coco Phytochemistry. ,vol. 10, pp. 2719- 2721 ,(1971) , 10.1016/S0031-9422(00)97270-4