Implant Debris from Total Joint Arthroplasties: Studies on the Mechanisms Responsible, the Amounts of Debris Generated, and the Implications in Loosening and Infection

摘要: The release of metallic and polymeric debris to the tissues fluids surrounding total joint replacement components is a significant problem with serious implications affecting longevity arthroplasty. Measurements levels suggests that common implant metals, titanium alloy generates more debris, though this conclusion based on measured in collected at revision from around implants which had already failed. Similar measurements performed synovial fluid samples obtained aspiration both well-fixed loose support finding. However, were much lower implants, suggesting failed replacements result rather than cause mechanical loosening itself. Based abundance generated wide range shape size may play important role eliciting deleterious biological reaction debris. Techniques for clinically improving situation exist, including component design minimize stresses associated damage polyethylene articulating surface.