High-frequency QRS analysis improves the specificity of exercise ECG testing in women referred for angiography.

摘要: Abstract Background Exercise ECG testing in women for the diagnosis of coronary artery disease (CAD) has a higher false-positive rate compared to men. Consequently, referred angiography following positive exercise test often have normal arteries or non-obstructive lesions. Analysis high-frequency components QRS complexes (HFQRS) been reported provide sensitive means detecting myocardial ischemia, independent gender. The aim present study was prospectively diagnostic performance HFQRS and conventional stress-induced ischemia angiography. Methods included 113 female patients (age 64 ± 9 years) non-urgent Patients performed symptom-limited treadmill prior High-resolution acquired during used both ST-segment analyses. determined by computerized analysis, measuring reduction intensity. HFQRS, analysis clinical interpretation were compared, using as gold standard. Results provided sensitivity 70% specificity 80% detection angiographically significant obstruction (≥ 70% stenosis single vessel ≥ 50% left main artery). more specific than (80% vs. 55%, P  Conclusions an adjunct technology stress testing, may improve value ECG, reduce number unnecessary imaging invasive procedures.