Insight into the Heparin–Toluidine Blue (C.I. Basic Blue 17) interaction

作者: L DILARIO , I FRANCOLINI , A MARTINELLI , A PIOZZI

DOI: 10.1016/J.DYEPIG.2008.07.015

关键词:

摘要: Abstract Heparin–Toluidine Blue (C.I. Basic 17) interaction was studied using UV–vis spectroscopic analysis of the titration functional groups present on polyanion chain. The study took into consideration both pH and relative amount dye as a function Heparin repeat unit number; formation dye/polysaccharide aggregate under same conditions structural models two types aggregates were proposed. As consequence such an investigation new determination methodology developed.

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